Roller compactors are widely used in industrial sectors like pharmaceuticals or cosmetics to create fine powders. These fine powders are then further processed to make the final product. The roller compactors for dry granulation force fine powder through two counter-rotating rolls. It is then further pressed into a solid compact like the sheet, strips, and flakes.
Different types of roller compactors
Roller compactors for dry granulation are classified into two types: those with a fixed gap and those with a floating gap. Their sole difference is how the shortest distance between the rolls is achieved.
The powder pulled into the compaction area between the rolls in fixed gap roller compactors is inconsistent. This enables various forces to be applied to the powder bed. This can result in significant variations in the ribbon and granule qualities.
Compared to the fixed gap compactor, the distance between the wheels in the floating gap compactor varies depending on the amount of powder to process. As a result, the force exerted on the powder stays unchanged. This guarantees that granule property variations are kept to a minimum.
The application of roller compactor in the pharmaceutical industry.
Roller compactors for dry granulation are widely used in the pharmaceutical industry. Some of the applications of roller compactors in this industry include the following.
- A good excipient material has excellent compatibility and flowability. The roller compactors are used to prepare such compressible excipients.
- Few drugs have tiny and inconsistent tap and bulk densities. These drugs are also very fine and inconsistent in size. Roll compaction is used to overcome these challenges if the material shows poor compatibility and flow properties.
- Extracting important components from dry herbal extracts possesses a high degree of hygroscopicity for their hydrophilic components, including organic acids and sugars. However, sometimes these extracts show poor compression and flow. Therefore, you will need compaction before tableting while extracting the herbal components.
If you need roller compactors for your work process, you must first determine whether you will need a fixed or floating type. It would be best if you only got a roller compactor from a highly reputable company to get a great product at a reasonable price.
